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George A Vielhauer Selected Research

Novobiocin (Streptonivicin)

2/2015Hsp90 C-terminal inhibitors exhibit antimigratory activity by disrupting the Hsp90α/Aha1 complex in PC3-MM2 cells.
10/2013Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
1/2010Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.

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George A Vielhauer Research Topics

Disease

11Neoplasms (Cancer)
07/2015 - 12/2007
3Prostatic Neoplasms (Prostate Cancer)
07/2015 - 01/2010
2Lung Neoplasms (Lung Cancer)
10/2013 - 06/2013
1Neoplasm Metastasis (Metastasis)
02/2015
1Leukemia L1210
06/2013
1Breast Neoplasms (Breast Cancer)
06/2013
1Carcinogenesis
12/2002

Drug/Important Bio-Agent (IBA)

5Heat-Shock Proteins (Heat-Shock Protein)IBA
07/2015 - 12/2009
4ProdrugsIBA
06/2013 - 12/2007
3LuciferasesIBA
07/2015 - 10/2011
3Proteins (Proteins, Gene)FDA Link
07/2015 - 12/2009
3Novobiocin (Streptonivicin)FDA Link
02/2015 - 01/2010
3Pharmaceutical PreparationsIBA
06/2013 - 10/2011
2AndrogensIBA
07/2015 - 10/2011
2Oncogene Proteins (Oncogene Protein)IBA
07/2015 - 10/2013
2Protein Isoforms (Isoforms)IBA
07/2015 - 02/2015
2Sulfhydryl Compounds (Thiols)IBA
11/2010 - 12/2007
1Antineoplastic Agents (Antineoplastics)IBA
07/2015
1Messenger RNA (mRNA)IBA
08/2014
1Biological ProductsIBA
06/2013
1DuocarmycinsIBA
06/2013
1indoleIBA
06/2013
1Molecular Chaperones (Chaperone, Molecular)IBA
10/2011
1F 4 (F-4)IBA
01/2010
1tanespimycin (17AAG)IBA
01/2010
1Prostaglandins FIBA
12/2002
1ProstaglandinsIBA
12/2002

Therapy/Procedure

3Therapeutics
07/2015 - 06/2013
1Drug Therapy (Chemotherapy)
06/2013